2m6g | pdb_00002m6g
From Proteopedia
Solution structure of cis(C2-P3) trans (D5-P6) form of lO959 in water
Template:ABSTRACT PUBMED 24115170
Function
[COW_CONLO] Activates high voltage-activated calcium channels (Cav). This activity is in contrast to other contryphans that inhibit high voltage-gated calcium channels.
About this Structure
2m6g is a 1 chain structure. Full experimental information is available from OCA.
Reference
- Sonti R, Gowd KH, Rao KN, Ragothama S, Rodriguez A, Perez JJ, Balaram P. Conformational Diversity in Contryphans from Conus Venom: cis-trans Isomerisation and Aromatic/Proline Interactions in the 23-Membered Ring of a 7-Residue Peptide Disulfide Loop. Chemistry. 2013 Nov 4;19(45):15175-89. doi: 10.1002/chem.201301722. Epub 2013 Sep, 23. PMID:24115170 doi:https://dx.doi.org/10.1002/chem.201301722
