4kcd | pdb_00004kcd

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Template:STRUCTURE 4kcd

Crystal Structure of the NMDA Receptor GluN3A Ligand Binding Domain Apo State

Template:ABSTRACT PUBMED 23972471

Function

[NMD3A_RAT] NMDA receptor subtype of glutamate-gated ion channels with reduced single-channel conductance, low calcium permeability and low voltage-dependent sensitivity to magnesium. Mediated by glycine. May play a role in the development of dendritic spines. May also play a role in PPP2CB-NMDAR mediated signaling mechanism.

About this Structure

4kcd is a 2 chain structure with sequence from Rattus norvegicus. Full crystallographic information is available from OCA.

Reference

  1. Yao Y, Belcher J, Berger AJ, Mayer ML, Lau AY. Conformational Analysis of NMDA Receptor GluN1, GluN2, and GluN3 Ligand-Binding Domains Reveals Subtype-Specific Characteristics. Structure. 2013 Oct 8;21(10):1788-99. doi: 10.1016/j.str.2013.07.011. Epub 2013, Aug 22. PMID:23972471 doi:https://dx.doi.org/10.1016/j.str.2013.07.011

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