4m67 | pdb_00004m67

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Template:STRUCTURE 4m67

Crystal structure of the human MLKL kinase-like domain

Template:ABSTRACT PUBMED 24095729

Function

[MLKL_HUMAN] Required for the execution of programmed necrosis.[1]

About this Structure

4m67 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Xie T, Peng W, Yan C, Wu J, Gong X, Shi Y. Structural Insights into RIP3-Mediated Necroptotic Signaling. Cell Rep. 2013 Oct 17;5(1):70-8. doi: 10.1016/j.celrep.2013.08.044. Epub 2013 Oct, 3. PMID:24095729 doi:https://dx.doi.org/10.1016/j.celrep.2013.08.044
  1. ↑ Wang Z, Jiang H, Chen S, Du F, Wang X. The mitochondrial phosphatase PGAM5 functions at the convergence point of multiple necrotic death pathways. Cell. 2012 Jan 20;148(1-2):228-43. doi: 10.1016/j.cell.2011.11.030. PMID:22265414 doi:https://dx.doi.org/10.1016/j.cell.2011.11.030

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