4mfe | pdb_00004mfe

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Template:STRUCTURE 4mfe

Structure of the carboxyl transferase domain from Rhizobium etli pyruvate carboxylase with 3-hydroxypyruvate

Template:ABSTRACT PUBMED 24157795

Function

[Q2K340_RHIEC] Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity).[PIRNR:PIRNR001594]

About this Structure

4mfe is a 4 chain structure. Full crystallographic information is available from OCA.

Reference

  1. Lietzan AD, St Maurice M. Insights into the carboxyltransferase reaction of pyruvate carboxylase from the structures of bound product and intermediate analogs. Biochem Biophys Res Commun. 2013 Oct 22. pii: S0006-291X(13)01738-5. doi:, 10.1016/j.bbrc.2013.10.066. PMID:24157795 doi:https://dx.doi.org/10.1016/j.bbrc.2013.10.066

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