2m8r | pdb_00002m8r

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Template:STRUCTURE 2m8r

Pre-Fusion Solution NMR Structure of Neuronal SNARE Syntaxin 1A

Template:ABSTRACT PUBMED 24218570

Function

[STX1A_RAT] Potentially involved in docking of synaptic vesicles at presynaptic active zones. May play a critical role in neurotransmitter exocytosis. May mediate Ca(2+)-regulation of exocytosis acrosomal reaction in sperm.

About this Structure

2m8r is a 1 chain structure with sequence from Buffalo rat. Full experimental information is available from OCA.

Reference

  1. Liang B, Kiessling V, Tamm LK. Prefusion structure of syntaxin-1A suggests pathway for folding into neuronal trans-SNARE complex fusion intermediate. Proc Natl Acad Sci U S A. 2013 Nov 11. PMID:24218570 doi:https://dx.doi.org/10.1073/pnas.1314699110

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OCA

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