3w2a | pdb_00003w2a

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Template:STRUCTURE 3w2a

Crystal structure of VirB core domain complexed with the cis-acting site upstream icsp promoter

Template:ABSTRACT PUBMED 23985969

Function

[VIRB_SHIFL] Transcription activator for the invasion antigens IpaB, IpaC and IpaD. VirB is itself regulated by VirF.

About this Structure

3w2a is a 3 chain structure with sequence from Shigella flexneri 2a. Full crystallographic information is available from OCA.

Reference

  1. Gao X, Zou T, Mu Z, Qin B, Yang J, Waltersperger S, Wang M, Cui S, Jin Q. Structural insights into VirB-DNA complexes reveal mechanism of transcriptional activation of virulence genes. Nucleic Acids Res. 2013 Dec 1;41(22):10529-41. doi: 10.1093/nar/gkt748. Epub 2013, Aug 27. PMID:23985969 doi:https://dx.doi.org/10.1093/nar/gkt748

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OCA

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