2rf3 | pdb_00002rf3
Crystal Structure of Tricyclo-DNA: An Unusual Compensatory Change of Two Adjacent Backbone Torsion Angles
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Overview
The crystal structure of a DNA duplex with tricyclo-DNA (tc-DNA) residues explains the increased RNA affinity of tc-DNA relative to DNA and tc-DNA's superior resistance to nucleases.
About this Structure
2RF3 is a Single protein structure of sequence from [1] with ZN and SPM as ligands. Known structural/functional Sites: AC1 and AC2. Full crystallographic information is available from OCA.
Reference
Crystal structure of tricyclo-DNA: an unusual compensatory change of two adjacent backbone torsion angles., Pallan PS, Ittig D, Heroux A, Wawrzak Z, Leumann CJ, Egli M, Chem Commun (Camb). 2008 Feb 21;(7):883-5. Epub 2007 Dec 21. PMID:18253536
Page seeded by OCA on Thu Feb 21 18:46:47 2008
