4i74 | pdb_00004i74

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Template:STRUCTURE 4i74

Crystal structure of the Trypanosoma brucei Inosine-Adenosine-Guanosine nucleoside hydrolase in complex with compound UAMC-00312 and allosterically inhibited by a Ni2+ ion

Template:ABSTRACT PUBMED 23897478

About this Structure

4i74 is a 1 chain structure with sequence from Tryb2. Full crystallographic information is available from OCA.

Reference

  1. Giannese F, Berg M, Van der Veken P, Castagna V, Tornaghi P, Augustyns K, Degano M. Structures of purine nucleosidase from Trypanosoma brucei bound to isozyme-specific trypanocidals and a novel metalorganic inhibitor. Acta Crystallogr D Biol Crystallogr. 2013 Aug;69(Pt 8):1553-66. doi:, 10.1107/S0907444913010792. Epub 2013 Jul 20. PMID:23897478 doi:https://dx.doi.org/10.1107/S0907444913010792

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