4nc3 | pdb_00004nc3
From Proteopedia
Crystal structure of the 5-HT2B receptor solved using serial femtosecond crystallography in lipidic cubic phase.
Function
[5HT2B_HUMAN] This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Plays a role in the regulation of impulsive behavior.
About this Structure
4nc3 is a 1 chain structure. Full crystallographic information is available from OCA.
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Barty, A.
- Basu, S.
- Beyerlein, K R.
- Boutet, S.
- Caffrey, M.
- Chapman, H N.
- Cherezov, V.
- Fromme, P.
- Fromme, R.
- GPCR, GPCR Network.
- Gati, C.
- Grotjohann, I.
- Han, G W.
- James, D.
- Katritch, V.
- Kirian, R A.
- Koglin, J E.
- Kupitz, C.
- Li, D.
- Liu, W.
- Messerschmidt, M.
- Nelson, G.
- Rendek, K N.
- Seibert, M M.
- Shah, S T.A.
- Spence, J C.H.
- Stevens, R C.
- Wacker, D.
- Wang, C.
- Wang, D.
- Weierstall, U.
- White, T A.
- Williams, G J.
- Zatsepin, N A.
- Electron transport
- Ergotamine
- Free electron laser
- Gpcr
- Gpcr network
- Human 5ht2b receptor
- Lipidic cubic phase
- Membrane
- Membrane protein
- Novel protein engineering
- Psi-biology
- Serial femtosecond crystallography
- Signaling protein
- Structural genomic
