2uvm | pdb_00002uvm
STRUCTURE OF PKBALPHA PH DOMAIN IN COMPLEX WITH A NOVEL INOSITOL HEADGROUP SURROGATE, BENZENE 1,2,3,4-TETRAKISPHOSPHATE
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Disease
Known diseases associated with this structure: Breast cancer, somatic OMIM:[164730], Colorectal cancer, somatic OMIM:[164730], Neutrophil immunodeficiency syndrome OMIM:[602049], Ovarian cancer, somatic OMIM:[164730], Schizophrenia, susceptibility to OMIM:[164730]
About this Structure
2UVM is a Single protein structure of sequence from Homo sapiens with NA and GVF as ligands. Active as Non-specific serine/threonine protein kinase, with EC number 2.7.11.1 Known structural/functional Site: AC1. Full crystallographic information is available from OCA.
Page seeded by OCA on Thu Feb 21 18:50:40 2008
Proteopedia Page Contributors and Editors (what is this?)
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- Homo sapiens
- Non-specific serine/threonine protein kinase
- Single protein
- Aalten, D M.F Van.
- Komander, D.
- Mills, S J.
- Potter, B V.L.
- Safrany, S T.
- Trussle, M N.
- GVF
- NA
- Apoptosis
- Atp-binding
- Cancer
- Carbohydrate metabolism
- Cell signalling
- Glucose metabolism
- Glycogen biosynthesis
- Glycogen metabolism
- Inositol
- Kinase
- Nuclear protein
- Nucleotide-binding
- Ph domain
- Phosphoinositide
- Phosphorylation
- Protein kinase b
- Serine/threonine-protein kinase
- Sugar transport
- Transferase
- Translation regulation
- Transport