2m5i | pdb_00002m5i
From Proteopedia
NMR structures of human apoptotic protein tBid in LPPG micelle
Function
[BID_HUMAN] The major proteolytic product p15 BID allows the release of cytochrome c (By similarity). Isoform 1, isoform 2 and isoform 4 induce ICE-like proteases and apoptosis. Isoform 3 does not induce apoptosis. Counters the protective effect of Bcl-2.[1]
About this Structure
2m5i is a 1 chain structure with sequence from Human. Full experimental information is available from OCA.
Reference
- Wang Y, Tjandra N. Structural insights of tBid, the caspase-8 activated Bid, and its BH3 domain. J Biol Chem. 2013 Oct 24. PMID:24158446 doi:https://dx.doi.org/10.1074/jbc.M113.503680
- ↑ Renshaw SA, Dempsey CE, Barnes FA, Bagstaff SM, Dower SK, Bingle CD, Whyte MK. Three novel Bid proteins generated by alternative splicing of the human Bid gene. J Biol Chem. 2004 Jan 23;279(4):2846-55. Epub 2003 Oct 28. PMID:14583606 doi:https://dx.doi.org/10.1074/jbc.M309769200
