4o38 | pdb_00004o38
From Proteopedia
Crystal structure of the human cyclin G associated kinase (GAK)
Function
[GAK_HUMAN] Associates with cyclin G and CDK5. Seems to act as an auxilin homolog that is involved in the uncoating of clathrin-coated vesicles by Hsc70 in non-neuronal cells. Expression oscillates slightly during the cell cycle, peaking at G1.[1]
About this Structure
4o38 is a 2 chain structure. This structure supersedes the now removed PDB entry 3ll6. Full crystallographic information is available from OCA.
Reference
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Non-specific serine/threonine protein kinase
- Arrowsmith, C H.
- Bountra, C.
- Chaikuad, A.
- Delft, F von.
- Edwards, A.
- Eswaran, J.
- Fedorov, O.
- Hatzos-Skintges, C.
- Joachimiak, A.
- King, O.
- Knapp, S.
- MCSG, Midwest Center for Structural Genomics.
- SGC, Structural Genomics Consortium.
- Weger, A.
- Weigelt, J.
- Zhang, R.
- Atp-binding
- Cell cycle
- Cell junction
- Clathrine
- Cyclin g
- Golgi apparatus
- Kinase
- Mcsg
- Membrane trafficking
- Midwest center for structural genomic
- Nucleotide-binding
- P53
- Phosphoprotein
- Protein kinase
- Protein structure initiative
- Psi-2
- Serine/threonine kinase
- Sgc
- Structural genomic
- Structural genomics consortium
- Transferase
