4lt6 | pdb_00004lt6

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Template:STRUCTURE 4lt6

Crystal Structure of human poly(A) polymerase gamma

Template:ABSTRACT PUBMED 24076191

Function

[PAPOG_HUMAN] Responsible for the post-transcriptional adenylation of the 3'-terminal of mRNA precursors and several small RNAs including signal recognition particle (SRP) RNA, nuclear 7SK RNA, U2 small nuclear RNA, and ribosomal 5S RNA.

About this Structure

4lt6 is a 2 chain structure with sequence from Human. Full crystallographic information is available from OCA.

Reference

  1. Yang Q, Nausch L, Martin G, Keller W, Doublie S. Crystal Structure of Human Poly(A) Polymerase Gamma Reveals a Conserved Catalytic Core for Canonical Poly(A) Polymerases. J Mol Biol. 2013 Sep 25. pii: S0022-2836(13)00609-8. doi:, 10.1016/j.jmb.2013.09.025. PMID:24076191 doi:https://dx.doi.org/10.1016/j.jmb.2013.09.025

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