4mhg | pdb_00004mhg

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Template:STRUCTURE 4mhg

Crystal structure of ETV6 bound to a specific DNA sequence

Template:ABSTRACT PUBMED 24333486

Function

[ETV6_MOUSE] Transcriptional repressor; binds to the DNA sequence 5'-CCGGAAGT-3'.

About this Structure

4mhg is a 3 chain structure. Full crystallographic information is available from OCA.

Reference

  1. De S, Chan AC, Coyne HJ 3rd, Bhachech N, Hermsdorf U, Okon M, Murphy ME, Graves BJ, McIntosh LP. Steric mechanism of auto-inhibitory regulation of specific and non-specific DNA binding by the ETS transcriptional repressor ETV6. J Mol Biol. 2013 Dec 11. pii: S0022-2836(13)00747-X. doi:, 10.1016/j.jmb.2013.11.031. PMID:24333486 doi:https://dx.doi.org/10.1016/j.jmb.2013.11.031

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OCA

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