3b0k | pdb_00003b0k
From Proteopedia
Crystal structure of alpha-lactalbumin
Template:ABSTRACT PUBMED 23155056
Function
[LALBA_CAPHI] Regulatory subunit of lactose synthase, changes the substrate specificity of galactosyltransferase in the mammary gland making glucose a good acceptor substrate for this enzyme. This enables LS to synthesize lactose, the major carbohydrate component of milk. In other tissues, galactosyltransferase transfers galactose onto the N-acetylglucosamine of the oligosaccharide chains in glycoproteins.
About this Structure
3b0k is a 2 chain structure with sequence from African dwarf goat. Full crystallographic information is available from OCA.
See Also
Reference
- Makabe K, Nakamura T, Kuwajima K. Structural insights into the stability perturbations induced by N-terminal variation in human and goat alpha-lactalbumin. Protein Eng Des Sel. 2013 Feb;26(2):165-70. doi: 10.1093/protein/gzs093. Epub, 2012 Nov 14. PMID:23155056 doi:https://dx.doi.org/10.1093/protein/gzs093
