2zya | pdb_00002zya

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Template:STRUCTURE 2zya

Dimeric 6-phosphogluconate dehydrogenase complexed with 6-phosphogluconate

Template:ABSTRACT PUBMED 19686854

Function

[6PGD_ECOLI] Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.

About this Structure

2zya is a 2 chain structure with sequence from Ecoli. Full crystallographic information is available from OCA.

See Also

Reference

  1. Chen YY, Ko TP, Chen WH, Lo LP, Lin CH, Wang AH. Conformational changes associated with cofactor/substrate binding of 6-phosphogluconate dehydrogenase from Escherichia coli and Klebsiella pneumoniae: Implications for enzyme mechanism. J Struct Biol. 2010 Jan;169(1):25-35. Epub 2009 Aug 15. PMID:19686854 doi:10.1016/j.jsb.2009.08.006

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