3fwn | pdb_00003fwn
From Proteopedia
Dimeric 6-phosphogluconate dehydrogenase complexed with 6-phosphogluconate and 2'-monophosphoadenosine-5'-diphosphate
Function
[6PGD_ECOLI] Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
About this Structure
3fwn is a 2 chain structure with sequence from Ecoli. Full crystallographic information is available from OCA.
See Also
Reference
- Chen YY, Ko TP, Chen WH, Lo LP, Lin CH, Wang AH. Conformational changes associated with cofactor/substrate binding of 6-phosphogluconate dehydrogenase from Escherichia coli and Klebsiella pneumoniae: Implications for enzyme mechanism. J Struct Biol. 2010 Jan;169(1):25-35. Epub 2009 Aug 15. PMID:19686854 doi:10.1016/j.jsb.2009.08.006
