2md8 | pdb_00002md8
From Proteopedia
NMR structure of Sp140 PHD finger cis conformer
Template:ABSTRACT PUBMED 24267382
Function
[SP140_HUMAN] Component of the nuclear body, also known as nuclear domain 10, PML oncogenic domain, and KR body. May be involved in the pathogenesis of acute promyelocytic leukemia and viral infection.
About this Structure
2md8 is a 1 chain structure with sequence from Human. Full experimental information is available from OCA.
Reference
- Zucchelli C, Tamburri S, Quilici G, Palagano E, Berardi A, Saare M, Peterson P, Bachi A, Musco G. Structure of human Sp140 PHD finger: an atypical fold interacting with Pin1. FEBS J. 2014 Jan;281(1):216-31. doi: 10.1111/febs.12588. Epub 2013 Nov 25. PMID:24267382 doi:https://dx.doi.org/10.1111/febs.12588
