3a8o | pdb_00003a8o

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Template:STRUCTURE 3a8o

Crystal structure of Nitrile Hydratase complexed with Trimethylacetamide

Template:ABSTRACT PUBMED 20221653

Function

[NHAA_RHOER] NHase catalyzes the hydration of various nitrile compounds to the corresponding amides. Industrial production of acrylamide is now being developed using some of the enzymes of this class. [NHAB_RHOER] NHase catalyzes the hydration of various nitrile compounds to the corresponding amides.

About this Structure

3a8o is a 2 chain structure with sequence from "mycobacterium_erythropolis"_gray_and_thornton_1928 "mycobacterium erythropolis" gray and thornton 1928. Full crystallographic information is available from OCA.

Reference

  1. Yamanaka Y, Hashimoto K, Ohtaki A, Noguchi K, Yohda M, Odaka M. Kinetic and structural studies on roles of the serine ligand and a strictly conserved tyrosine residue in nitrile hydratase. J Biol Inorg Chem. 2010 Mar 10. PMID:20221653 doi:10.1007/s00775-010-0632-3

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