4jg4 | pdb_00004jg4

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Template:STRUCTURE 4jg4

Ligand concentration regulates the pathways of coupled protein folding and binding

Template:ABSTRACT PUBMED 24364358

Function

[G4ENZ9_BACIU] RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity).[HAMAP-Rule:MF_00227][SAAS:SAAS000100_004_060152]

About this Structure

4jg4 is a 1 chain structure. Full crystallographic information is available from OCA.

Reference

  1. Daniels KG, Tonthat NK, McClure DR, Chang YC, Liu X, Schumacher MA, Fierke CA, Schmidler SC, Oas TG. Ligand Concentration Regulates the Pathways of Coupled Protein Folding and Binding. J Am Chem Soc. 2014 Jan 9. PMID:24364358 doi:https://dx.doi.org/10.1021/ja4086726

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