3ai8 | pdb_00003ai8
From Proteopedia
Cathepsin B in complex with the nitroxoline
Function
[CATB_HUMAN] Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis.
About this Structure
3ai8 is a 2 chain structure with sequence from Human. Full crystallographic information is available from OCA.
See Also
Reference
- Mirkovic B, Renko M, Turk S, Sosic I, Jevnikar Z, Obermajer N, Turk D, Gobec S, Kos J. Novel Mechanism of Cathepsin B Inhibition by Antibiotic Nitroxoline and Related Compounds. ChemMedChem. 2011 May 20. doi: 10.1002/cmdc.201100098. PMID:21598397 doi:10.1002/cmdc.201100098
