3ecs | pdb_00003ecs
From Proteopedia
Crystal structure of human eIF2B alpha
Disease
[EI2BA_HUMAN] Cree leukoencephalopathy;Late infantile CACH syndrome;Ovarioleukodystrophy. The disease is caused by mutations affecting the gene represented in this entry.
Function
[EI2BA_HUMAN] Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP.
About this Structure
3ecs is a 8 chain structure with sequence from Human. Full crystallographic information is available from OCA.
See Also
Reference
- Hiyama TB, Ito T, Imataka H, Yokoyama S. Crystal structure of the alpha subunit of human translation initiation factor 2B. J Mol Biol. 2009 Oct 2;392(4):937-51. Epub 2009 Jul 23. PMID:19631657 doi:10.1016/j.jmb.2009.07.054
