4ad6 | pdb_00004ad6

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Template:STRUCTURE 4ad6

Synthesis and SAR of guanine based analogues for HPPK inhibitors

Template:ABSTRACT PUBMED 23565155

About this Structure

4ad6 is a 2 chain structure. Full crystallographic information is available from OCA.

Reference

  1. Chhabra S, Barlow N, Dolezal O, Hattarki MK, Newman J, Peat TS, Graham B, Swarbrick JD. Exploring the chemical space around 8-mercaptoguanine as a route to new inhibitors of the folate biosynthesis enzyme HPPK. PLoS One. 2013;8(4):e59535. doi: 10.1371/journal.pone.0059535. Epub 2013 Apr 2. PMID:23565155 doi:https://dx.doi.org/10.1371/journal.pone.0059535

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