2r0k | pdb_00002r0k

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Template:STRUCTURE 2r0k

Protease domain of HGFA with inhibitor Fab58

Template:ABSTRACT PUBMED 18077410

Function

[HGFA_HUMAN] Activates hepatocyte growth factor (HGF) by converting it from a single chain to a heterodimeric form.

About this Structure

2r0k is a 3 chain structure with sequence from [1] and Human. Full crystallographic information is available from OCA.

See Also

Reference

  1. Wu Y, Eigenbrot C, Liang WC, Stawicki S, Shia S, Fan B, Ganesan R, Lipari MT, Kirchhofer D. Structural insight into distinct mechanisms of protease inhibition by antibodies. Proc Natl Acad Sci U S A. 2007 Dec 11;104(50):19784-9. Epub 2007 Dec 5. PMID:18077410

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OCA

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