4irz | pdb_00004irz

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Template:STRUCTURE 4irz

Crystal structure of A4b7 headpiece complexed with Fab Natalizumab

Template:ABSTRACT PUBMED 24047894

About this Structure

4irz is a 3 chain structure with sequence from European rabbit and Human. Full crystallographic information is available from OCA.

Reference

  1. Yu Y, Schurpf T, Springer TA. How natalizumab binds and antagonizes alpha4 integrins. J Biol Chem. 2013 Nov 8;288(45):32314-25. doi: 10.1074/jbc.M113.501668. Epub 2013, Sep 18. PMID:24047894 doi:https://dx.doi.org/10.1074/jbc.M113.501668

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OCA

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