4am3 | pdb_00004am3

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Template:STRUCTURE 4am3

Crystal structure of C. crescentus PNPase bound to RNA

Template:ABSTRACT PUBMED 22724061

Function

[PNP_CAUCR] Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity).

About this Structure

4am3 is a 7 chain structure with sequence from Cauce and Escherichia coli. Full crystallographic information is available from OCA.

Reference

  1. Hardwick SW, Gubbey T, Hug I, Jenal U, Luisi BF. Crystal structure of Caulobacter crescentus polynucleotide phosphorylase reveals a mechanism of RNA substrate channelling and RNA degradosome assembly. Open Biol. 2012 Apr;2(4):120028. PMID:22724061 doi:10.1098/rsob.120028

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