4cih | pdb_00004cih

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Template:STRUCTURE 4cih

Structure of LntA-K180D-K181D from Listeria monocytogenes

Template:ABSTRACT PUBMED 24449750

Function

[LNTA_LISMO] Relieves the repression of host cell immune response genes (interferon-stimulated genes) by blocking the recruitment of host BAHD1 to these genes. May modulate interferon-mediated immune response to control bacterial colonization of the host.

About this Structure

4cih is a 4 chain structure. Full crystallographic information is available from OCA.

Reference

  1. Lebreton A, Job V, Ragon M, Le Monnier A, Dessen A, Cossart P, Bierne H. Structural Basis for the Inhibition of the Chromatin Repressor BAHD1 by the Bacterial Nucleomodulin LntA. MBio. 2014 Jan 21;5(1). pii: e00775-13. doi: 10.1128/mBio.00775-13. PMID:24449750 doi:https://dx.doi.org/10.1128/mBio.00775-13

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OCA

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