4bva | pdb_00004bva
From Proteopedia
Cristal structure of the NADPH-T3 form of mouse Mu-crystallin.
Template:ABSTRACT PUBMED 24467707
Function
[CRYM_MOUSE] Specifically catalyzes the reduction of imine bonds in brain substrates that may include cystathionine ketimine (CysK) and lanthionine ketimine (LK). Binds thyroid hormone which is a strong reversible inhibitor. Presumably involved in the regulation of the free intracellular concentration of triiodothyronine and access to its nuclear receptors (By similarity).
About this Structure
4bva is a 2 chain structure. Full crystallographic information is available from OCA.
Reference
- Borel F, Hachi I, Palencia A, Gaillard MC, Ferrer JL. Crystal Structure of mouse Mu-crystallin complexed with NADPH and the T3 thyroid hormone. FEBS J. 2014 Jan 27. doi: 10.1111/febs.12726. PMID:24467707 doi:https://dx.doi.org/10.1111/febs.12726
