3kko | pdb_00003kko
From Proteopedia
Crystal structure of M-Ras P40D/D41E/L51R in complex with GppNHp
Function
[RASM_MOUSE] May serve as an important signal transducer for a novel upstream stimuli in controlling cell proliferation. Weakly activates the MAP kinase pathway (By similarity).
About this Structure
3kko is a 3 chain structure with sequence from Lk3 transgenic mice. Full crystallographic information is available from OCA.
Reference
- Shima F, Ijiri Y, Muraoka S, Liao J, Ye M, Araki M, Matsumoto K, Yamamoto N, Sugimoto T, Yoshikawa Y, Kumasaka T, Yamamoto M, Tamura A, Kataoka T. Structural basis for conformational dynamics of GTP-bound Ras protein. J Biol Chem. 2010 Jul 16;285(29):22696-705. Epub 2010 May 17. PMID:20479006 doi:10.1074/jbc.M110.125161
