2mcw | pdb_00002mcw

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Template:STRUCTURE 2mcw

Solid-state NMR structure of piscidin 3 in aligned 3:1 phosphatidylcholine/phosphoglycerol lipid bilayers

Template:ABSTRACT PUBMED 24410116

Function

[PISC3_MORCS] Exhibits broad-spectrum antimicrobial activity against both Gram-positive and Gram-negative bacteria. Has hemolytic activity.

About this Structure

2mcw is a 1 chain structure. Full experimental information is available from OCA.

Reference

  1. Perrin BS Jr, Tian Y, Fu R, Grant CV, Chekmenev EY, Wieczorek WE, Dao AE, Hayden RM, Burzynski CM, Venable RM, Sharma M, Opella SJ, Pastor RW, Cotten ML. High-Resolution Structures and Orientations of Antimicrobial Peptides Piscidin 1 and Piscidin 3 in Fluid Bilayers Reveal Tilting, Kinking, and Bilayer Immersion. J Am Chem Soc. 2014 Jan 22. PMID:24410116 doi:https://dx.doi.org/10.1021/ja411119m

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