4mxi | pdb_00004mxi

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Template:STRUCTURE 4mxi

ClpP Ser98dhA

Template:ABSTRACT PUBMED 24106749

Function

[CLPP_STAA8] Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity).

About this Structure

4mxi is a 7 chain structure with sequence from Staa8. Full crystallographic information is available from OCA.

Reference

  1. Gersch M, Kolb R, Alte F, Groll M, Sieber SA. Disruption of oligomerization and dehydroalanine formation as mechanisms for ClpP protease inhibition. J Am Chem Soc. 2013 Oct 9. PMID:24106749 doi:https://dx.doi.org/10.1021/ja4082793

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