2mdq | pdb_00002mdq

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Template:STRUCTURE 2mdq

A Novel 4/7-Conotoxin LvIA from Conus lividus that Selectively Blocks 3 2 vs. 6/3 2 3 Nicotinic Acetylcholine Receptors

Template:ABSTRACT PUBMED 24398291

Function

[L8BU87_CONLI] Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them (By similarity).[RuleBase:RU004345]

About this Structure

2mdq is a 1 chain structure. Full experimental information is available from OCA.

Reference

  1. Luo S, Zhangsun D, Schroeder CI, Zhu X, Hu Y, Wu Y, Weltzin MM, Eberhard S, Kaas Q, Craik DJ, McIntosh JM, Whiteaker P. A novel alpha4/7-conotoxin LvIA from Conus lividus that selectively blocks alpha3beta2 vs. alpha6/alpha3beta2beta3 nicotinic acetylcholine receptors. FASEB J. 2014 Jan 7. PMID:24398291 doi:https://dx.doi.org/10.1096/fj.13-244103

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