4mjw | pdb_00004mjw
From Proteopedia
Crystal Structure of Choline Oxidase in Complex with the Reaction Product Glycine Betaine
Function
[CHOX_ARTGO] Catalyzes the two-step oxidative conversion of choline to glycine-betaine with betaine aldehyde as an intermediate. Glycine-betaine accumulates to high levels in the cytoplasm of cells to prevent dehydration and plasmolysis in adverse hyperosmotic environments. Accepts either choline or the reaction intermediate betaine-aldehyde as substrate.[1]
About this Structure
4mjw is a 2 chain structure. Full crystallographic information is available from OCA.
Reference
- ↑ Rand T, Halkier T, Hansen OC. Structural characterization and mapping of the covalently linked FAD cofactor in choline oxidase from Arthrobacter globiformis. Biochemistry. 2003 Jun 17;42(23):7188-94. PMID:12795615 doi:https://dx.doi.org/10.1021/bi0274266
