3ikp | pdb_00003ikp

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Template:STRUCTURE 3ikp

Crystal structure of inositol phosphate bound trimeric human lung surfactant protein D

Template:ABSTRACT PUBMED 19799916

Function

[SFTPD_HUMAN] Contributes to the lung's defense against inhaled microorganisms. May participate in the extracellular reorganization or turnover of pulmonary surfactant. Binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties.

About this Structure

3ikp is a 3 chain structure with sequence from Human. Full crystallographic information is available from OCA.

Reference

  1. Shrive AK, Martin C, Burns I, Paterson JM, Martin JD, Townsend JP, Waters P, Clark HW, Kishore U, Reid KB, Greenhough TJ. Structural characterisation of ligand-binding determinants in human lung surfactant protein D: influence of Asp325. J Mol Biol. 2009 Dec 11;394(4):776-88. Epub 2009 Sep 30. PMID:19799916 doi:10.1016/j.jmb.2009.09.057

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