4nlg | pdb_00004nlg
From Proteopedia
Y-family DNA polymerase chimera Dbh-Dpo4(243-245)-Dbh
Template:ABSTRACT PUBMED 24415763
Function
[DPO4_SULAC] Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis (By similarity).
About this Structure
4nlg is a 3 chain structure. Full crystallographic information is available from OCA.
Reference
- Mukherjee P, Wilson RC, Lahiri I, Pata JD. Three Residues of the Interdomain Linker Determine the Conformation and Single-Base Deletion Fidelity of Y-family Translesion Polymerases. J Biol Chem. 2014 Jan 10. PMID:24415763 doi:https://dx.doi.org/10.1074/jbc.M113.537860
