4ole | pdb_00004ole

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Template:STRUCTURE 4ole

Crystal structure of a neighbor of BRCA1 gene 1 (NBR1) from Homo sapiens at 2.52 A resolution

Function

[NBR1_HUMAN] Acts probably as a receptor for selective autophagosomal degradation of ubiquitinated targets.[1]

About this Structure

4ole is a 4 chain structure. Full crystallographic information is available from OCA.

Reference

  1. ↑ Kirkin V, Lamark T, Sou YS, Bjorkoy G, Nunn JL, Bruun JA, Shvets E, McEwan DG, Clausen TH, Wild P, Bilusic I, Theurillat JP, Overvatn A, Ishii T, Elazar Z, Komatsu M, Dikic I, Johansen T. A role for NBR1 in autophagosomal degradation of ubiquitinated substrates. Mol Cell. 2009 Feb 27;33(4):505-16. doi: 10.1016/j.molcel.2009.01.020. PMID:19250911 doi:10.1016/j.molcel.2009.01.020

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