4l2b | pdb_00004l2b

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Template:STRUCTURE 4l2b

X-ray structure of the C57S mutant of the iron superoxide dismutase from Pseudoalteromonas haloplanktis

Template:ABSTRACT PUBMED 24440460

Function

[SODF_PSEHT] Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.[1]

About this Structure

4l2b is a 2 chain structure. Full crystallographic information is available from OCA.

Reference

  1. Merlino A, Russo Krauss I, Castellano I, Ruocco MR, Capasso A, De Vendittis E, Rossi B, Sica F. Structural and denaturation studies of two mutants of a cold adapted superoxide dismutase point to the importance of electrostatic interactions in protein stability. Biochim Biophys Acta. 2014 Mar;1844(3):632-40. doi: 10.1016/j.bbapap.2014.01.007., Epub 2014 Jan 17. PMID:24440460 doi:https://dx.doi.org/10.1016/j.bbapap.2014.01.007
  1. ↑ Castellano I, Di Maro A, Ruocco MR, Chambery A, Parente A, Di Martino MT, Parlato G, Masullo M, De Vendittis E. Psychrophilic superoxide dismutase from Pseudoalteromonas haloplanktis: biochemical characterization and identification of a highly reactive cysteine residue. Biochimie. 2006 Oct;88(10):1377-89. Epub 2006 Apr 27. PMID:16713057 doi:https://dx.doi.org/S0300-9084(06)00055-1

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