4irb | pdb_00004irb
From Proteopedia
Crystal Structure of Vaccinia Virus Uracil DNA Glycosylase Mutant del171-172D4
Function
[UNG_VACCA] Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. Also part of a heterodimeric processivity factor which potentiates the DNA polymerase activity. Binds to DNA.
About this Structure
4irb is a 4 chain structure. Full crystallographic information is available from OCA.
Reference
- Sartmatova D, Nash T, Schormann N, Nuth M, Ricciardi R, Banerjee S, Chattopadhyay D. Crystallization and preliminary X-ray diffraction analysis of three recombinant mutants of Vaccinia virus uracil DNA glycosylase. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 Mar 1;69(Pt 3):295-301., doi: 10.1107/S1744309113002716. Epub 2013 Feb 23. PMID:23519808 doi:https://dx.doi.org/10.1107/S1744309113002716
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Uracil-DNA glycosylase
- Chattopadhyay, D.
- Nuth, M.
- Ricciardi, R P.
- Sartmatova, D.
- Schormann, N.
- Zhukovskaya, N.
- Beta- sheets at n- and c-terminus
- Binding partners a20 and dna
- Component of processivity factor
- Dimeric assembly
- Dna repair hydrolase
- Hydrolase
- Parallel beta-sheet of 4 strands in the order 2134
- Viral protein
