4c5w | pdb_00004c5w

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Template:STRUCTURE 4c5w

Three dimensional structure of human gamma-butyrobetaine hydroxylase in complex with 4-(Ethyldimethylammonio)butanoate

Template:ABSTRACT PUBMED 24571165

Function

[BODG_HUMAN] Catalyzes the formation of L-carnitine from gamma-butyrobetaine.

About this Structure

4c5w is a 1 chain structure. Full crystallographic information is available from OCA.

Reference

  1. Tars K, Leitans J, Kazaks A, Zelencova D, Liepinsh E, Kuka J, Makrecka M, Lola D, Andrianovs V, Gustina D, Grinberga S, Liepinsh E, Kalvinsh I, Dambrova M, Loza E, Pugovics O. Targeting carnitine biosynthesis: discovery of new inhibitors against gamma-butyrobetaine hydroxylase. J Med Chem. 2014 Feb 26. PMID:24571165 doi:https://dx.doi.org/10.1021/jm401603e

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OCA

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