3u2b | pdb_00003u2b

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Template:STRUCTURE 3u2b

Structure of the Sox4 HMG domain bound to DNA

Template:ABSTRACT PUBMED 22181698

Function

[SOX4_MOUSE] Transcriptional activator that binds with high affinity to the T-cell enhancer motif 5'-AACAAAG-3' motif.

About this Structure

3u2b is a 3 chain structure with sequence from Lk3 transgenic mice. Full crystallographic information is available from OCA.

Reference

  1. Jauch R, Ng CK, Narasimhan K, Kolatkar PR. Crystal structure of the Sox4 HMG/DNA complex suggests a mechanism for the positional interdependence in DNA recognition. Biochem J. 2011 Dec 19. PMID:22181698 doi:10.1042/BJ20111768

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