4duq | pdb_00004duq

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Template:STRUCTURE 4duq

The Structure of Ca2+-loaded S100A2 at 1.3A resolution

Template:ABSTRACT PUBMED 22394450

Function

[S10A2_HUMAN] May act as a modulator against excess calcium accumulation in normal human mammary epithelial cells. May also play a role in suppressing tumor cell growth.[1]

About this Structure

4duq is a 2 chain structure with sequence from Human. This structure supersedes the now removed PDB entry 3n22. Full crystallographic information is available from OCA.

See Also

Reference

  1. Koch M, Fritz G. The Structure of Ca(2+) -loaded S100A2 at 1.3 A resolution. FEBS J. 2012 Mar 6. doi: 10.1111/j.1742-4658.2012.08556.x. PMID:22394450 doi:10.1111/j.1742-4658.2012.08556.x
  1. ↑ Lee SW, Tomasetto C, Swisshelm K, Keyomarsi K, Sager R. Down-regulation of a member of the S100 gene family in mammary carcinoma cells and reexpression by azadeoxycytidine treatment. Proc Natl Acad Sci U S A. 1992 Mar 15;89(6):2504-8. PMID:1372446

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