4jbv | pdb_00004jbv

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Template:STRUCTURE 4jbv

Calcium-Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1) in complex with inhibitor UW1268

Template:ABSTRACT PUBMED 24531197

About this Structure

4jbv is a 1 chain structure. Full crystallographic information is available from OCA.

Reference

  1. Vidadala RS, Ojo KK, Johnson SM, Zhang Z, Leonard SE, Mitra A, Choi R, Reid MC, Keyloun KR, Fox AM, Kennedy M, Silver-Brace T, Hume JC, Kappe S, Verlinde CL, Fan E, Merritt EA, Van Voorhis WC, Maly DJ. Development of potent and selective Plasmodium falciparum calcium-dependent protein kinase 4 (PfCDPK4) inhibitors that block the transmission of malaria to mosquitoes. Eur J Med Chem. 2014 Mar 3;74:562-73. doi: 10.1016/j.ejmech.2013.12.048. Epub, 2014 Jan 11. PMID:24531197 doi:https://dx.doi.org/10.1016/j.ejmech.2013.12.048

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