4ltv | pdb_00004ltv

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Template:STRUCTURE 4ltv

Crystal structure of epi-isozizaene synthase from Streptomyces coelicolor A3(2)

Template:ABSTRACT PUBMED 24517311

Function

[CYC1_STRCO] Catalyzes the cyclization of farnesyl diphosphate (FPP) to the sesquiterpene epi-isozizaene.

About this Structure

4ltv is a 1 chain structure. Full crystallographic information is available from OCA.

Reference

  1. Li R, Chou WK, Himmelberger JA, Litwin KM, Harris GG, Cane DE, Christianson DW. Reprogramming the Chemodiversity of Terpenoid Cyclization by Remolding the Active Site Contour of epi-Isozizaene Synthase. Biochemistry. 2014 Feb 25;53(7):1155-68. doi: 10.1021/bi401643u. Epub 2014 Feb, 11. PMID:24517311 doi:https://dx.doi.org/10.1021/bi401643u

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