3cbk | pdb_00003cbk
From Proteopedia
chagasin-cathepsin B
Function
[CATB_HUMAN] Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis.
About this Structure
3cbk is a 2 chain structure. Full crystallographic information is available from OCA.
See Also
Reference
- Redzynia I, Ljunggren A, Abrahamson M, Mort JS, Krupa JC, Jaskolski M, Bujacz G. Displacement of the occluding loop by the parasite protein, chagasin, results in efficient inhibition of human cathepsin B. J Biol Chem. 2008 Aug 15;283(33):22815-25. Epub 2008 May 30. PMID:18515357 doi:10.1074/jbc.M802064200
