3o7q

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Template:STRUCTURE 3o7q

Crystal structure of a Major Facilitator Superfamily (MFS) transporter, FucP, in the outward conformation

Template:ABSTRACT PUBMED 20877283

Function

[FUCP_ECOLI] Mediates the uptake of L-fucose across the boundary membrane with the concomitant transport of protons into the cell (symport system). Can also transport L-galactose and D-arabinose, but at reduced rates compared with L-fucose. Is not able to transport L-rhamnose and L-arabinose.[1]

About this Structure

3o7q is a 1 chain structure with sequence from Ecoli. Full crystallographic information is available from OCA.

See Also

Reference

  1. Dang S, Sun L, Huang Y, Lu F, Liu Y, Gong H, Wang J, Yan N. Structure of a fucose transporter in an outward-open conformation. Nature. 2010 Oct 7;467(7316):734-8. Epub 2010 Sep 26. PMID:20877283 doi:10.1038/nature09406
  1. ↑ Bradley SA, Tinsley CR, Muiry JA, Henderson PJ. Proton-linked L-fucose transport in Escherichia coli. Biochem J. 1987 Dec 1;248(2):495-500. PMID:2829831

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