3oqc | pdb_00003oqc

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Template:STRUCTURE 3oqc

Ubiquitin-fold modifier 1 Specific Protease, UfSP2

Template:ABSTRACT PUBMED 21228277

Function

[UFSP2_MOUSE] Thiol protease which recognizes and hydrolyzes the peptide bond at the C-terminal Gly of UFM1, an ubiquitin-like modifier protein bound to a number of target proteins. Does not hydrolyze SUMO1 or ISG15 ubiquitin-like proteins.[1] [2]

About this Structure

3oqc is a 2 chain structure with sequence from Lk3 transgenic mice. Full crystallographic information is available from OCA.

Reference

  1. Ha BH, Jeon YJ, Shin SC, Tatsumi K, Komatsu M, Tanaka K, Watson CM, Wallis G, Chung CH, Kim EE. Structure of ubiquitin-fold modifier 1-specific protease UfSP2. J Biol Chem. 2011 Mar 25;286(12):10248-57. Epub 2011 Jan 12. PMID:21228277 doi:https://dx.doi.org/10.1074/jbc.M110.172171
  1. ↑ Kang SH, Kim GR, Seong M, Baek SH, Seol JH, Bang OS, Ovaa H, Tatsumi K, Komatsu M, Tanaka K, Chung CH. Two novel ubiquitin-fold modifier 1 (Ufm1)-specific proteases, UfSP1 and UfSP2. J Biol Chem. 2007 Feb 23;282(8):5256-62. Epub 2006 Dec 20. PMID:17182609 doi:https://dx.doi.org/M610590200
  2. ↑ Ha BH, Jeon YJ, Shin SC, Tatsumi K, Komatsu M, Tanaka K, Watson CM, Wallis G, Chung CH, Kim EE. Structure of ubiquitin-fold modifier 1-specific protease UfSP2. J Biol Chem. 2011 Mar 25;286(12):10248-57. Epub 2011 Jan 12. PMID:21228277 doi:https://dx.doi.org/10.1074/jbc.M110.172171

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