4nc5 | pdb_00004nc5

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Template:STRUCTURE 4nc5

Human sialidase 2 in complex with 2,3-difluorosialic acid (covalent intermediate)

Template:ABSTRACT PUBMED 24591206

Function

[NEUR2_HUMAN] Hydrolyzes sialylated compounds.

About this Structure

4nc5 is a 1 chain structure with sequence from Human. Full crystallographic information is available from OCA.

See Also

Reference

  1. Buchini S, Gallat FX, Greig IR, Kim JH, Wakatsuki S, Chavas LM, Withers SG. Tuning mechanism-based inactivators of neuraminidases: mechanistic and structural insights. Angew Chem Int Ed Engl. 2014 Mar 24;53(13):3382-6. doi: 10.1002/anie.201309675., Epub 2014 Mar 3. PMID:24591206 doi:https://dx.doi.org/10.1002/anie.201309675

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OCA

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