4mlv | pdb_00004mlv
From Proteopedia
Crystal Structure of Bacillus megaterium porphobilinogen deaminase
Function
[Q8GCA8_BACME] Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity).[HAMAP-Rule:MF_00260][SAAS:SAAS022418_004_010364]
About this Structure
4mlv is a 1 chain structure. Full crystallographic information is available from OCA.
Reference
- Azim N, Deery E, Warren MJ, Wolfenden BA, Erskine P, Cooper JB, Coker A, Wood SP, Akhtar M. Structural evidence for the partially oxidized dipyrromethene and dipyrromethanone forms of the cofactor of porphobilinogen deaminase: structures of the Bacillus megaterium enzyme at near-atomic resolution. Acta Crystallogr D Biol Crystallogr. 2014 Mar;70(Pt 3):744-51. doi:, 10.1107/S139900471303294X. Epub 2014 Feb 15. PMID:24598743 doi:https://dx.doi.org/10.1107/S139900471303294X
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Hydroxymethylbilane synthase
- Akhtar, M.
- Azim, N.
- Coker, A.
- Cooper, J B.
- Deery, E.
- Erskine, P.
- Warren, M J.
- Wood, S P.
- Dipyrromethane cofactor
- Domains 1 and 2 resemble the fold of type ii periplasmic binding protein
- Porphobilinogen deaminase
- Pyrrole polymerisation
- Tetrapyrrole biosynthesis
- Three-domain fold
- Transferase
