2mgs | pdb_00002mgs

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Template:STRUCTURE 2mgs

Solution structure of CXCL5

Function

[CXCL5_HUMAN] Involved in neutrophil activation. In vitro, ENA-78(8-78) and ENA-78(9-78) show a threefold higher chemotactic activity for neutrophil granulocytes.[1]

About this Structure

2mgs is a 2 chain structure. Full experimental information is available from OCA.

Reference

  1. ↑ Wuyts A, Govaerts C, Struyf S, Lenaerts JP, Put W, Conings R, Proost P, Van Damme J. Isolation of the CXC chemokines ENA-78, GRO alpha and GRO gamma from tumor cells and leukocytes reveals NH2-terminal heterogeneity. Functional comparison of different natural isoforms. Eur J Biochem. 1999 Mar;260(2):421-9. PMID:10095777

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