1chz | pdb_00001chz
From Proteopedia
A NEW NEUROTOXIN FROM BUTHUS MARTENSII KARSCH
Function
[SCM2_MESMA] Binds to sodium channels (Nav) and inhibits the inactivation of the activated channels, thereby blocking neuronal transmission. This toxin is active against mammals and insects.
About this Structure
1chz is a 1 chain structure with sequence from Mesobuthus martensii. Full crystallographic information is available from OCA.
Reference
- He XL, Deng JP, Wang M, Zhang Y, Wang DC. Structure of a new neurotoxin from the scorpion Buthus martensii Karsch at 1.76 A. Acta Crystallogr D Biol Crystallogr. 2000 Jan;56(Pt 1):25-33. PMID:10666623
